Although the majority of TE changes are identified in the AT2 cells, the AM cells also show TEs association with metalloproteases (MMP7 and 14), interleukin (IL15RA), chemokine (CCL22), and osteopontin (SPP1), which are all implicated in the development of IPF [45]. The gene discussed is MMP7; the disease is idiopathic pulmonary fibrosis.