Although the majority of TE changes are identified in the AT2 cells, the AM cells also show TEs association with metalloproteases (MMP7 and 14), interleukin (IL15RA), chemokine (CCL22), and osteopontin (SPP1), which are all implicated in the development of IPF [45]. This evidence concerns the gene IL15RA and idiopathic pulmonary fibrosis.