NPLOC4 and myopia: Two genes encoding components of ubiquitin-protein-ligase complex, beta-transducin repeat containing E3 ubiquitin protein ligase (BTRC) and ubiquitin recognition factor NPL4 homolog (NPLOC4), confirm the importance of the protein ubiquitination pathway in myopia development identified by several studies [12, 112–114, 153–157].