Approximately 75% of pathways linked to form-deprivation myopia development (27 out of 36) were also associated with contrast perception, including tRNA charging, HIPPO signaling, AMPK signaling, NER pathway, IGF-1 signaling, protein kinase A signaling, role of JAK2 in hormone-like cytokine signaling, relaxin signaling, and PPARα/RXRα activation. This evidence concerns the gene JAK2 and myopia.