Many factors are implicated in the link of central obesity with pathogenesis of hypertension, such as overactivation of the sympathetic nervous system (SNS) by insulin also present in obese patients [4], leptin, activation of the renin–angiotensin–aldosterone system (RAAS), sodium excretion, pressure natriuresis, and salt sensitivity [5, 6]. Here, REN is linked to Hypertension.