Both h16f and ABBV-176 bind comparably to cells expressing human wild-type PRLR including a high expressing tumor cell line (T47D Fig. 1C), a low expressing tumor cell line (MCF-7, Fig. 1D) and HEK-293 cells engineered to express human PRLR (Fig. 1E). The gene discussed is PRLR; the disease is neoplasm.