APC and neoplasm: Among these, a total of 21 BSAGs (ADAM11, APC, BRCA2, CDH11, CERS2, DSC3, DTWD1, EPHB6, ERCC3, ERCC4, FANCC, HELQ, HRG, ING1, INTS6, POU6F2, STAG1, TEP1, TET1, TRMT2A and ZFHX3) were identified to be tumor suppressors according to the literature or CGC database (Table 1).