ACE2 and infection: Resultsshowed that both NhPV and Suramin block SARS-CoV SP-mediated infection in293T-ACE2 cells (Fig 3F).All of these results demonstrate that both NhPV and Suramin exhibit stronginhibitory effect on infections mediated by SPΔCD614-PVs,SPΔCG614-PVs and SARS-CoV SP-PVs.