ABO antigens influence several biomarkers and is closely related to insulin resistance and the development of type 2 diabetes, such as E-selectin, P-selectin, tumor necrosis factor-α, soluble intercellular adhesion molecule-1 and interleukin-6.[15,16] Some studies have explored the relationship between ABO blood type and diabetes, but the findings are mostly inconsistent.[14,17,18] However, most of the studies on ABO blood group and its relationship with GDM are also inconsistent.[14]. This evidence concerns the gene ABO and gestational diabetes.