WT1 and Nephropathy: For example, specialists from the Denver Children's Hospital described a case of mutation in exon 6 of WT1 in a patient with karyotype 46, XY, incomplete androgen insensitivity syndrome, and bilateral WT without nephrotic syndrome.[41] A group of authors from Germany also noted the absence of nephropathy.[42] Among 53 patients included in their study, 3 did not suffer from proteinuria.