DICER1 and Ataxia: Previous reports have shown that the conditional Dicer deletion driven by hGFAP-Cre or mGFAP-Cre results in severe functional deficits, such as ataxia and seizures, and premature deaths of the mutant mice [16], while the Dicer deletion in the developing CNS causes memory and motor coordination deficits in adulthood without severe dysfunctions.