In past reports, a large number of inflammatory indicators had been reported to have close relation to the prognosis of patients with intrahepatic cholangiocarcinoma, including platelet to lymphocyte ratio (PLR), neutrophil to lymphocyte ratio (NLR), lymphocyte to monocyte ratio (LMR), C‐reactive protein (CRP), and Glasgow Prognostic Score (GPS).33, 34, 35. This evidence concerns the gene CRP and intrahepatic cholangiocarcinoma.