Taken together with the evidence that HSCs predominately secrete TIMPs contributing to liver fibrosis[47] whereas pharmacological inhibition of A‐FABP attenuates the hepatic expression of TIMP‐1 in diet‐induced obese mice,[10] this evidence support the detrimental action of A‐FABP in liver fibrosis is at least partially exerted through its regulation on TGFβ1 expression. This evidence concerns the gene FABP4 and Hepatic fibrosis.