These data suggested the beneficial effect of BMS309403 on liver fibrosis is at least partially attributable to its alleviation on the LSEC capillarization and the subsequent HSC activation through its suppression on JNK/c‐Jun pathway thus reducing the expression of BDL‐induced TGFβ1 and its downstream signaling. This evidence concerns the gene TGFB1 and Hepatic fibrosis.