Interestingly, in a tumor environment, the degree of NF‐κB activation inversely correlates with the degree of aneuploidy (Taylor et al, 2018), raising the possibility that silencing of the aneuploidy‐induced immunogenicity could be a non‐cell autonomous event in cancer, perhaps induced by cells in the tumor microenvironment. Here, NFKB1 is linked to neoplasm.