IL1B and COVID-19: Cytokine storm might play an important role in initiating and promoting thrombosis in arteries and veins.9 High levels of cytokines were detected in the plasma of critically ill patients with COVID-19.1,15 COVID-19 might lead to microthrombi in small vessels in the lung, kidney and heart by activation of IL-1B and IL-6 and inhibition of anti-thrombin 3 and might cause respiratory decompensation by abnormal immune response.