PTAFR and ischemia: The main findings of this study are: (1) ADTM reduces the infarct size and improves cardiac function in MIR rats; (2) ADTM inhibits myocardial cell apoptosis and inflammation in ischemia/reperfusion myocardium; (3) ADTM inhibits cardiomyocytes apoptosis and inflammation in hypoxia/re-oxygenation-induced cardiomyocytes by down-regulation of PAFR.