CASP3 and non-small cell lung carcinoma: U0126 and SB203580 did not affect cell viability, cell cycle arrest, and cleaved caspase-3 levels in PB01-treated NSCLC cells; SP600125 decreased cell viability, cell cycle arrest, and cleaved caspase-3 levels in PB01-treated NSCLC cells (Figure S2b–d).