This includes the gene encoding the gamma chain of the high-affinity IgE receptor (FCER1G, z = 4.74, PTWAS = 2.13E−6) on chromosome 1q23.3 playing a key role in allergic reactions and DM1 protein kinase (DMPK, z = 4.83, PTWAS = 1.37E−6) on chromosome 19q13.32 with cellular antioxidant and pro-survival properties18. The gene discussed is DMPK; the disease is allergic disease.