STAT3 and hepatocellular carcinoma: A recent study showed that acylcarnitine profiles can be used as biomarkers for obesity-driven HCC, pinpointed a serum metabolite, oleoylcarnitine (C18:1 carnitine), which was found in this study, as one of the biomarkers for NAFLD and HCC, and revealed the mechanism of actions of oleoylcarnitine through STAT3 pathway activation31.