Post-hoc lookups of known ALS genes that might be associated with TD revealed that an F-Box protein-encoding gene FBXO15, chemo/neurokine encoding gene FAM19A1, and neuropeptide encoding gene, NPS. Proteinopathies commonly implicated in neurodegenerative conditions have been proposed to also underlie TD61,62. Here, NPS is linked to proteostasis deficiencies.