Serum CPSF2-Ab levels were associated primarily with AIS and DM and partly with TIA, cCI, esophageal squamous cell carcinoma, and rheumatoid arthritis but not with AMI, CKD, CVD, colorectal carcinoma, gastric cancer, breast cancer, pancreatic cancer, Sjögren’s syndrome, SLE, or ulcerative colitis (Figs. 2, 3, 4; Tables 2, 3, and 4; Supplementary Tables S1 and S2). The gene discussed is CPSF2; the disease is diabetes mellitus.