Specimens from human breast adenocarcinoma, lung carcinoma, glioblastoma, angiosarcoma, and Kaposi’s sarcoma showed the presence of p‐EphrinB (range 12–54%), p‐SHP2 (14–58%), and p‐TIE2 (16–61%) in a proportion of tumor vascular endothelial cells and Ang2 in a proportion of the CD31− tumor cells (2–63%) (Abdul Pari et al,2020). The gene discussed is PTPN11; the disease is angiosarcoma.