NLRP3 and acute lymphoblastic leukemia: Among the mRNAs co-expressed with the top 3 key lncRNAs, we found 3 genes (ACTN1, TNFRSF21 and NLRP3) significantly affected the survival situation of ALL patients and the log-rank p-values were 0.0054, 0.0155 and 0.0369, respectively (Fig 6).