To further investigate the mechanisms by which RhoA regulated Tgf-β1 release and allergic airway inflammation, we analyzed the transcriptional profiles of AT2 cells (Figure 5A) isolated from the lungs of RhoAfl/fl and Sftpc-cre;RhoAfl/fl mouse models of asthma as illustrated in Figure 3C. This evidence concerns the gene RHOA and asthma.