HDAC6 and cancer: As such, HDAC6 plays a key role in microtubule dynamicsand chaperone activities, DNA damage repair pathways, and oncogenicstress responses through the regulation of cell migration, immune-cellsynapse formation, protein trafficking, and degradation.11−13 The upregulation of HDAC6 activity has been directly correlatedwith cellular proliferation, metastasis, and mitosis, highlightingthe impact of this epigenetic regulator in cancer pathogenesis.11,12,14