Intriguingly, many of these Hippo‐YAP target genes can be found in the mesenchymal GBM gene signature and are also up‐regulated as the result of the GBM proneural‐to‐mesenchymal transition (e.g., ANGPTL4, COL1A1/2, CTGF, CYP1B1, ITGA1, LIF, and THBS1) (Minata et al, 2019). This evidence concerns the gene ITGA1 and glioblastoma.