Although the positivity of anti-RIB-P in SLE patients with NPLE exceeded the positivity of anti-RIB-P in SLE patients without NPLE, considering the low number of patients with SLE with NPLE as well, it was not statistically possible to investigate the correlation between the MFI of TIM-3 on TIM-3+PD-1+ NK cells and anti-RIB-P in SLE patients with NPLE. The gene discussed is HAVCR2; the disease is systemic lupus erythematosus.