The 25 strongest predictors for PFD from the univariate analysis are displayed in Table 3, 11 of which were included in the multivariable model: SBP (up to 130 mmHg), NYHA class III/IV vs. I/II, LVEF (up to 40%), ischemic etiology, a diagnosis of HF for > 5 years, HF duration > 1 and ≤ 5 years, bundle branch block (BBB) on ECG, serum albumin concentration (30–45 g/L), creatinine (1.0–2.5 mg/dL) and chloride (90–106 mmol/L), and plasma NT-proBNP (log-transformed). Here, NPPB is linked to hydrops fetalis.