In particular, according to the revised 4th edition of “WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues”, the non-nodal MCL, which was indolent, had negative Sox11 expression, therefore Sox11high MCL patients might have inferior OS in a cohort with both non-nodal and classic MCL patients9,23,24. Here, SOX11 is linked to mantle cell lymphoma.