In total, PLIER identified 137 rearrangements involving MYC, BCL2, and BCL6: 56 MYC rearrangements (in 49 lymphoma samples), 39 BCL2 rearrangements (in 34 samples), and 42 BCL6 rearrangements (in 40 samples) (Fig. 2A). The gene discussed is BCL6; the disease is lymphoma.