When measuring the effect size of plasma NfL against the PD group (Fig. 2B), large effects sizes were observed for atypical parkinsonian disorders (CBS/PSP, Hedges g = 2.0; MSA, Hedges g = 1.4) and also large effect sizes for some cognitive impairment disorders (VaD, Hedges g = 1.88; FTD, Hedges g = 1.4; PDD/DLB, Hedges g = 1.1, AD dementia, Hedges g = 1.0). The gene discussed is NEFL; the disease is Parkinson disease.