Plasma NfL also performed well in identifying atypical parkinsonian disorders from PD patients with very high specificity in the KCL cohort (AUC = 86%; sensitivity = 56%; specificity = 89%) which was observed in the Lund cohort for both CBS/PSP (AUC = 95%; sensitivity = 51%; specificity = 100%) and MSA (AUC = 88%; sensitivity = 57%; specificity = 90%). The gene discussed is NEFL; the disease is Parkinson disease.