PTPRC and head and neck squamous cell carcinoma: We first analyzed scRNAseq data generated from purified CD45+ cells (i.e. all immune cells) from a total of 63 samples, including paired PBL and TIL from 18 patients with HPV– HNSCC and 9 patients with HPV+ HNSCC (Supplementary Table 1, Cohort 1).