CHRNE and Alzheimer disease: In the 3’-UTR region of CHRNE (Cholinergic Receptor Nicotinic Epsilon Subunit), rs72835061 (MAF = 0.085) was associated with a 1.09-fold increased risk of AD (95% CI [1.06–1.11], p = 1.5 × 10−10, Fig. 2e).