The second regression analysis showed that the combination of IL-10 and zLnEM2/KOR were the best predictors of prediabetes+IR versus prediabetes−IR (χ2 = 14.780, df = 7, p = 0.031, Nagelkerke = 0.364) with an accuracy of 71.2%, sensitivity of 74.4%, and specificity of 72.7%. The gene discussed is IL10; the disease is prediabetes syndrome.