Previous studies have reported a correlation between programmed death-1/ligand-1 (PD-1/PD-L1) and immune activity in tumors in triple-negative breast cancer [19]; Moreover, a large number of studies have shown that ssGSEA and ESTIMATE are highly reliable in the evaluation of tumor immune stratification and immune invasion analysis [21, 57–60]. Here, CD274 is linked to triple-negative breast carcinoma.