In accordance with our results, downregulation of MEG3 and overexpression of H19 lncRNAs were found by several research groups in association with various neoplasms and the link of these lncRNAs with p53 and pRb pathways underlines their significance in E6 and E7 mediated transformation [19, 65, 66]. This evidence concerns the gene TP53 and neoplasm.