LncRNA TUG1 (taurine up-regulated gene 1), a lncRNA which locates on human chromosome 22q12.2 and plays an oncogenic role in many kinds of human cancers, was reported to alleviate the histological damage of diabetic nephropathy in diabetic mice by enhancing the expression of PGC-1α in podocytes[15]. This evidence concerns the gene TUG1 and diabetic kidney disease.