Over-expression of SIRPA WT reduced infection by JUNV-C1, LCMV and VSV viruses (Fig 3B) and pseudoviruses bearing viral glycoproteins from MACV and SARS-CoV-2 (Fig 3C), while infection levels in ΔCyto-expressing cells were similar to those observed for the pcDNA empty vector control (Fig 3B and 3C). This evidence concerns the gene SIRPA and infection.