SLC5A2 and heart failure: The aforementioned beneficial findings of SGLT2 inhibitors in HFrEF were corroborated in patients with acute decompensated heart failure in the Dutch multicentre trial EMPA-RESPONSE-AHF (Randomized, Double-blind, Placebo-controlled, Multicentre Pilot Study on the Effects of Empagliflozin on Clinical Outcomes in Patients with Acute Decompensated Heart Failure) and the multinational SOLOIST-WHF (Effect of Sotagliflozin on Cardiovascular Events in Patients with Type 2 Diabetes Post Worsening Heart Failure) trial [48, 49].