The significant increase in the level of interleukin such as IL-1, IL-4, IL-6 was recorded in colon cancer patients (17.26 ± 2.49 pg/ml, 32.18 ± 1.45 pg/ml, 28.26 ± 1.88 pg/ml) as compared to controls (6.35 ± 1.07 pg/ml, 21.25 ± 2.18 pg/ml, 9.58 ± 3.33 pg/ml), respectively. The gene discussed is IL4; the disease is malignant colon neoplasm.