Recentexperiments of our group showed that TGFβ2, SMAD5, ALK1, JAG1, VEGFR2 andTIMP2 genes, which are known to play a role in angiogenesis and fibrosis,presented imbalanced expression in endothelial cells from T1DM mice (9). This evidence concerns the gene TGFB2 and type 1 diabetes mellitus.