BRCA1 and prostate adenocarcinoma: Surprisingly, we also found associations with lower neoantigen loads for DDR alterations, including germline ATM variants in BRCA, prostate adenocarcinoma (PRAD), LUAD, and BLCA (FDR < 0.011; Table S3), and somatic BRCA1, ATM, and ATR mutations in OV, liver hepatocellular carcinoma (LIHC), and COADREAD (FDR < 0.043; Figures 2B and 2C; Table S3), respectively.