For patients with failed response to immunosuppression, immunoadsorption can be used to remove the auto-antibodies to FVIII.29 Treatment of the underlying cause—for instance in our patient, treating LPL with chemoimmunotherapy—or stopping a drug associated with AHA, may also lead to cure of AHA and reduce the risk of recurrence. The gene discussed is LPL; the disease is autoimmune hemolytic anemia.