In autosomal dominant polycystic kidney disease (ADPKD), the majority of mutations occur in PKD1 and PKD2, which encode polycystin 1 and polycystin 2, which form a complex and function at the primary cilium (Freedman et al., 2013; Cai et al., 2014; Walker et al., 2019). Here, PKD2 is linked to autosomal dominant polycystic kidney disease.