Thus, it is comprehensible why an overexpression of ODC has been proven in CRC (Goodwin et al., 2011) and neuroblastoma (Evageliou and Hogarty, 2009; Battaglia et al., 2014), confirmed that ODC might promote the colorectal cancer progress (Patil et al., 2016). The gene discussed is ODC1; the disease is colorectal cancer.