DYT-THAP1 iPSCs were derived from two affected patients and one family member with reduced penetrance (Zittel et al., 2010) carrying a frameshift mutation p.Lys158Asnfs∗23 manifesting in writer’s dystonia followed by laryngeal dystonia and a missense mutation p.Arg13His leading to generalized dystonia. The gene discussed is THAP1; the disease is generalized dystonia.