CXCL1 and ovarian neoplasm: It has been reported that through highly releasing chemokine (C-X-C motif) ligand 1 (CXCL1), CXCL2, and IL-8, MSCs manipulate metabolic programs to promote M2 macrophages differentiation, leading to abolition of their tumoricidal functions, thus facilitating the acquisition of chemoresistance in ovarian tumor cells.