In gastric cancer (GC), evidence presents that MSCs secreted TGF-β1 promotes fatty acid oxidation (FAO) to support stemness features and drug resistance, which is mediated by activating SMAD2 and SMAD3 and promoting lncRNA MACC1AS1 expression (He et al., 2019). The gene discussed is MACC1-AS1; the disease is gastric cancer.