PSMB6 and lysinuric protein intolerance: Efferocytosis is the process by which macrophages and other phagocytic cells remove apoptotic cells; recently Demy et al. showed that y+LAT1 is expressed shortly after efferocytosis in microglia and other tissue resident macrophages allowing them to preserve their own viability during phagocytosis, defects in macrophage phagocytic function could contribute to both neurologic and immunologic finding in patients with LPI (79).