HOXA13 and neoplasm: Even more remarkably, although the tumor sizes of 5-FU groups were smaller than those of CON groups, 5-FU impeded tumor formation of shHOXA13 group more significantly (402.19 to 128.92 mm3; −67.95%), compared with shNC group (529.75 to 448.38 mm3; −15.36%), suggesting that suppression of HOXA13 improved the sensitivity of MKN45 cells to 5-FU (Figures 6A, B).