This analysis revealed that a significant down-regulation of HEPH mRNA expression levels is found in several other malignancies such as BLCA (bladder urothelial carcinoma), BRCA (breast invasive carcinoma), COAD (colon adenocarcinoma), KICH (kidney chromophobe), KIRP (kidney renal clear cell carcinoma), LIHC (liver hepatocellular carcinoma), LUAD (lung adenocarcinoma), LUSC (lung squamous adenocarcinoma), PRAD (prostate adenocarcinoma), READ (rectum adenocarcinoma), and UCEC (uterine corpus endometrial carcinoma) compared to the corresponding normal tissues (Figure 1A). This evidence concerns the gene HEPH and rectum adenocarcinoma.