CD4 and neoplasm: In LGG, the expression level of ARID5A was not significantly correlated with CD8+ T cell, positively correlated with B cells (cor = 0.43, P = 5.62e-23), CD4+ T cells (cor = 0.597, P = 2.48e-47), macrophages (cor = 0.518, P = 7.70e-34), neutrophils (cor = 0.647, P = 9.77e-58), and dendritic cells (cor = 0.614, P = 1.28e-50), and negatively correlated with tumor purity (cor = -0.168,P = 2.19e-04) (Figure 8A).