CD4 and glioblastoma: In GBM, the results showed that there was no significant correlation between the expression level of ARID5A and infiltration of B cells, CD8+ T cells, and macrophages, and the expression level of ARID5A was positively correlated with CD4+ T cells (cor = 0.105, P = 3.22e-02), neutrophils (cor = 0.119, P = 1.47e-02), and dendritic cells (cor = 0.338, P = 1.25e-12) but negatively correlated with tumor purity (cor = -0.193, P = 6.94e-05)(Figure 8A).