In an extensive analysis regarding pancreatic cancer, PDX1, MNX1, HNF4G, HNF4A, HNF1B, HNF1A, FOXA2, FOXA3, and HES1 were proposed as the key TFs associated with the pancreatic progenitor subtype (76). This evidence concerns the gene HNF4A and familial pancreatic carcinoma.